Medical and Psychological Distress in Male COVID-19 Survivors with Lung Damage
https://doi.org/10.21603/sibscript-2025-27-2-149-162
EDN: oujdwa
Abstract
During the COVID-19 pandemic, men proved to be more susceptive to the virus and demonstrated a more severe disease progress, which led to stress and anxiety. This research describes the factors affecting the stress severity in men as part of mental and somatic status during two years after lung damage induced by COVID-19. It included 41 male survivors (55 ± 11 y.o.) of COVID-19. The respondents were diagnosed for anxiety (GAD-7), depression (PHQ-9), and stress (PSS-10), as well as examined by a cardiologist 3, 12, and 26 months after recovery. After 26 months, their emotional-personal sphere was examined for anxiety (ITT), coping (SSP), distress (SCL-90-R), and personality traits (5PFQ). While the body mass index had increased, the severity of anxiety, depression, and stress remained the same. A strong distress was detected in 31.7% of former COVID-19 patients with prevailing confrontation and escape-avoidance coping. This index correlated with such factors as extraversion vs. introversion (r=0.356, p=0.022) and emotionality vs. restraint (r=0.535, p<0.001). Three months after recovery, the stress severity increased as a result of anxiety. One year after recovery, it depended on the intensity of depression and lung damage in the acute period. Two years after recovery, it increased at high personality anxiety and low planning coping. The overall distress index correlated with personality anxiety and body mass index three months after recovery. The severity of stress did not exceed the normal stress level, while every third man in this group showed signs of distress. The intensity of stress reaction during two years after recovery depended on the degree of anxiety and depression. Anxiety and depression proved to be significant factors increasing the stress reaction intensity during two years after recovery from COVID-19. The distress factors included strong confrontation and escape-avoidance strategies, as well as such personality traits as emotionality, extraversion, and anxiety.
About the Authors
O. A. GuskovaRussian Federation
Olga A. Guskova
Tyumen
Scopus Author ID: 57304726400
Competing Interests:
The authors declared no potential conflict of interests regarding the research, authorship, and / or publication of this article
B. Yu. Prilensky
Russian Federation
Boris Yu. Prilensky
Tyumen
Scopus Author ID: 57330662000
Competing Interests:
The authors declared no potential conflict of interests regarding the research, authorship, and / or publication of this article
I. Ya. Stoyanova
Russian Federation
Irina Ya. Stoyanova
Tomsk
Scopus Author ID: 57193702114
Competing Interests:
The authors declared no potential conflict of interests regarding the research, authorship, and / or publication of this article
E. I. Yaroslavskaya
Russian Federation
Elena I. Yaroslavskaya
Tyumen
Scopus Author ID: 36459379400
Competing Interests:
The authors declared no potential conflict of interests regarding the research, authorship, and / or publication of this article
K. S. Avdeeva
Russian Federation
Kseniya S. Avdeeva
Tyumen
Scopus Author ID: 57426927100
Competing Interests:
The authors declared no potential conflict of interests regarding the research, authorship, and / or publication of this article
T. I. Petelina
Russian Federation
Tatyana I. Petelina
Tyumen
Scopus Author ID: 6507194861
Competing Interests:
The authors declared no potential conflict of interests regarding the research, authorship, and / or publication of this article
References
1. Ababkov V. A, Barisnikov K., Vorontzova-Wenger O. V., Gorbunov I. A., Kapranova S. V., Pologaeva E. A., Stuklov K. A. Validation of the Russian version of the questionnaire "Scale of perceived stress-10". Vestnik of Saint Petersburg University. Series 16. Psychology. Pedagogy, 2016, (2): 6–15. (In Russ.) https://elibrary.ru/ualwvl
2. Alenina O. K., Didenko A. V., Bokhan N. A. Characteristics of the spectrum of psychopathological manifestations in patients who have suffered COVID-19 infection. Bulletin of Medical Science, 2021, (1): 39–44. (In Russ.) https://elibrary.ru/hvoobc
3. Bizuk A. P., Wasserman L. I., Iovlev B. V. Application of the Integrative Anxiety Test (IAT). St. Petersburg: BPRI, 2005, 23. (In Russ.)
4. Bykhovets Yu. V. Stress of invisible information threats and its consequences. Counseling Psychology and Psychotherapy, 2023, 31(3): 132–166. (In Russ.) doi: 10.17759/cpp.2023310307
5. Bykhovets Yu. V., Padun M. A. Personal anxiety and emotion regulation in the context of study of post-traumatic stress. Clinical Psychology and Special Education, 2019, 8(1): 78–89. (In Russ.) doi: 10.17759/cpse.2019080105
6. Vasin G. M., Lobaskova M. M. The nature of the correlation between temperament and emotional and behavioral problems. Teoreticheskaya i eksperimentalnaya psikhologiya, 2015, 8(4): 103–114. (In Russ.) https://elibrary.ru/vrdhqp
7. Wasserman L. I., Iovlev B. V., Isaeva E. R., Trifonova E. A., Shchelkova O. Yu., Novozhilova M. Y. Methods for psychological diagnosis of ways of coping with stressful and problematic situations of the individual. St. Petersburg: BPRI, 2009, 38. (In Russ.)
8. Golskaya A. I., Mirzoeva R. K., Chernik O. V., Osipova A. S., Berdysh D. S. Sleep disorders and the main causes of insomnia. Mezhdunarodnyi nauchno-issledovatelskii zhurnal, 2021, (4-2): 108–112. (In Russ.)] https://elibrary.ru/itbbca
9. Grekhov R. A., Suleymanova G. P., Adamovich E. I. The role of anxiety in psycho-physiology of stress. Volgogradskogo gosudarstvennogo universiteta. Seriia 11: Estestvennye nauki, 2017, 7(1): 57–66. (In Russ.) doi: 10.15688/jvolsu11.2017.1.7
10. Demina N. S., Glaseva M. A. The correlation between emotional intelligence and anxiety in clinical psychology students. Psikhologiia, sotsiologiia i pedagogika, 2018, (4). (In Russ.) URL: https://psychology.snauka.ru/2018/04/8547 (accessed 20 Nov 2024). https://elibrary.ru/xnspsp
11. Ekimova V. I., Rozenova M. I., Litvinova A. V., Koteneva A. V. The fear traumatization: Psychological consequences of COVID-19 pandemic. Sovremennaya zarubezhnaya psikhologiya, 2021, 10(1): 27–38. (In Russ.) doi: 10.17759/jmfp.2021100103
12. Kamalov А. А., Nesterova O. Yu., Mareev V. Yu., Orlova Ia. A., Mareev Yu. V., Begrambekova Yu L., Pavlova Z. Sh., Plisyk A. G., Samokhodskaya L. M., Mershina E. A., Ohobotov D. A., Strigunov A. A., Tsurskaya D. D. Androgenic status of men with severe COVID-19: The role of testosterone and dihydrotestosterone [within the program FOUNDER (features of a new coronavirus infection course and options therapy depending on the androgenic status)]. Urologiia, 2023, (3): 78–86. (In Russ.) doi: 10.18565/urology.2023.3.78-86
13. Konevtsev I. V., Rodionova E. A. Extraversion and neuroticism as choice factors for coping strategies. Problems of theory and practice of modern psychology : Proc. All-Russian (with Intern. Participation) Sci.-Prac. Conf., Irkutsk, 29–30 Apr 2022. Irkutsk: ISU, 2022, 66–69. (In Russ.) https://elibrary.ru/akxhzy
14. Kuftyak E. V., Bekhter A. A. Stress and proactive coping behavior during COVID-19 pandemic: An online survey. Meditsinskaia psikhologiia v Rossii, 2020, 12(6). (In Russ.) URL: http://medpsy.ru/mprj/archiv_global/2020_6_65/nomer05.php (accessed 8 Nov 2024). https://elibrary.ru/zpryhs
15. Lipunova O. V. Emotions, behavior and personality as a psychological problem. Modern problems of science and education, 2014, 6. (In Russ.) URL: https://science-education.ru/ru/article/view?id=15507 (accessed 18 Nov 2024). https://elibrary.ru/tgrcff
16. Mishkevich A. M. Extroversion in different theories of personality. Penza psychological newsletter, 2019, (1): 52–69. (In Russ.) doi: 10.17689/psy-2019.1.4
17. Morozova M. A., Alekseev A. A., Rupchev G. E. Psychological distress and its significance for practicing doctor (in example of neurological practice). Nevrologiia i revmatologiia. Prilozhenie k zhurnalu Consilium Medicum, 2016, (2): 85–89. (In Russ.) https://elibrary.ru/yosooz
18. Murtazina I. R. Perception of daily stressors and coping strategies among residents of Saint-Petersburg and Arkhangelsk: Comparative analysis. World of Science. Pedagogy and psychology, 2018, (6). (In Russ.) URL: https://mir-nauki.com/PDF/79PSMN618.pdf (accessed 4 Dec 2024). https://elibrary.ru/yyjbyd
19. Nikitina D. A. Distress and psychopathological symptoms in somatic disease: Features of manifestation within the limits of the norm. World of Science. Pedagogy and psychology, 10(4). (In Russ.) URL: https://mir-nauki.com/PDF/47PSMN422.pdf (accessed 4 Dec 2024). https://elibrary.ru/huribz
20. Novoselova E. N. Impact of the COVID-19 pandemic on social health-saving practices and mental health of Russian citizens. Vestnik Moskovskogo universiteta. Serija 18. Sociologija i politologija, 2022, 28(1): 238–259. (In Russ.) doi: 10.24290/1029-3736-2022-28-1-238-259
21. Obnosov V. N. Anxiety as a manifestation of stress. Nauka i Obrazovanie, 2023, 6(1). (In Russ.) URL: http://opusmgau.ru/index.php/see/article/view/5517/5438 (accessed 18 Nov 2024). https://elibrary.ru/bzjbne
22. Smoleva E. O. Social stress and its coping strategies: Analysis of concepts and model. Social Area, 2020, 6(3). (In Russ.) doi: 10.15838/sa.2020.3.25.3
23. Solovieva N. V., Makarova E. V., Kichuk I. V. "Coronavirus syndromе": Prevention of phsychotrauma caused by COVID-19. RMJ, 2020, (9): 18–22. (In Russ.) https://elibrary.ru/jlqcan
24. Staniszewska Z. Stress, person, personality. From distress to eustress. Studia Humanitatis, 2020, 1: 16. (In Russ.) URL: https://st-hum.ru/sites/st-hum.ru/files/pdf/staniszewska_z.pdf (accessed 18 Nov 2024). https://elibrary.ru/qmlqrx
25. Stoyanova I. Ya., Gutkevich E. V., Lebedeva V. F., Ivanova A. A., Bokhan N. A. Psychological factors causing transnational hazard to the public mental health during a pandemic. Siberian Herald of Psychiatry and Addiction Psychiatry, 2022, (1): 46–56. (In Russ.) doi: 10.26617/1810-3111-2022-1(114)-46-56
26. Tarabarina N. V. Practical work on the psychology of post-traumatic stress. St. Petersburg: Piter, 2001, 272. (In Russ.) https://elibrary.ru/vojuuf
27. Troshikhina E. G., Manukyan V. R. Anxiety and stable emotional states in the structure of psycho-emotional wellbeing. Vestnik of Saint Petersburg University. Psychology and Education, 2017, 7(3): 211–223. (In Russ.) https://elibrary.ru/ztlsqf
28. Khromov A. B. Five-factor personality questionnaire. Kurgan: Kurgan State University, 2000, 23. (In Russ.)
29. Akil H., Nestler E. J. The neurobiology of stress: Vulnerability, resilience, and major depression. Proceeding of the National Academy of Sciences of the United States of America, 2023, 120(49). doi: 10.1073/pnas.2312662120
30. Cholankeril R., Xiang E., Badr H. Gender differences in coping and psychological adaptation during the COVID-19 pandemic. International Journal of Environmental Research and Public Health, 2023, 20(2). doi: 10.3390/ijerph20020993
31. DiSabato D. J., Nemeth D. P., Liu X., Witcher K. G., O’Neil S. M., Oliver B., Bray C. E., Sheridan J. F., Godbout J. P., Quan N. Interleukin-1 receptor on hippocampal neurons drives social withdrawal and cognitive deficits after chronic social stress. Molecular Psychiatry, 2021, 26: 4770–4782. doi: 10.1038/s41380-020-0788-3
32. Donzella S. M., Kohler L. N., Crane T. E., Jacobs E. T., Ernst K. C., Bell M. L., Catalfamo C. J., Begay R., Pogreda-Brown K., Farland L. V. COVID-19 infection, the COVID-19 pandemic, and changes in sleep. Frontiers in Public Health, 2021, 9. doi: 10.3389/fpubh.2021.795320
33. Fairweather D., Beetler D. J., Di Florio D. N., Musigk N., Heidecker B., Cooper L. T. Jr. COVID-19, myocarditis and pericarditis. Circulation Research, 2023, 132(10): 1302–1319. doi: 10.1161/CIRCRESAHA.123.321878
34. Gewirtz-Meydan A., Lassri D. A profile analysis of COVID-19 stress-related reactions: The importance of early childhood abuse, psychopathology, and interpersonal relationships. Child Abuse & Neglect, 2022, 130(1). doi: 10.1016/j.chiabu.2021.105442
35. Hassamal S. Chronic stress, neuroinflammation, and depression: An overview of pathophysiological mechanisms and emerging anti-inflammatories. Frontiers in Psychiatry, 2023, 14. doi: 10.3389/fpsyt.2023.1130989
36. Kempuraj D., Selvakumar G. P., Ahmed M. E., Raikwar S. P., Thangavel R., Khan A., Zaheer S. A., Iyer S. S., Burton C., James D., Zaheer A. COVID-19, Mast Cells, Cytokine Storm, Psychological Stress, and Neuroinflammation. The Neuroscientist, 2020, 26(5-6): 402–414. doi: 10.1177/1073858420941476
37. Lakhan R., Agrawal A., Sharma M. Prevalence of depression, anxiety, and stress during COVID-19 pandemic. Journal of Neurosciences in Rural Practice, 2020, 11(4): 519–525. doi: 10.1055/s-0040-1716442
38. Le L. T. H., Hoang T. N. A., Nguyen T. T., Dao T. D., Do B. N., Pham K. M., Vu V. H., Pham L. V., Nguyen L. T. H., Nguyen H. C., Tran T. V., Nguyen T. H., Nguyen A. T., Nguyen H. V., Nguyen P. B., Nguyen H. T. T., Pham T. T. M., Le T. T., Nguyen T. T. P., Tran C. Q., Quach H. L., Nguyen K. T., Duong T. V. Sex differences in clustering unhealthy lifestyles among survivors of COVID-19: Latent class analysis. JMIR Public Health and Surveillance, 2024, 10. doi: 10.2196/50189
39. Mandelli L., Milaneschi Y., Hiles S., Serretti A., Penninx B. W. Unhealthy lifestyle impacts on biological systems involved in stress response: Hypothalamic-pituitary-adrenal axis, inflammation and autonomous nervous system. International Clinical Psychopharmacology, 2023, 38(3): 127–135. doi: 10.1097/YIC.0000000000000437
40. Osborne M. T., Shin L. M., Mehta N. N., Pitman R. K., Fayad Z. A., Tawakol A. Disentangling the links between psychosocial stress and cardiovascular disease. Circulation: Cardiovascular Imaging, 2020, 13(8). doi: 10.1161/CIRCIMAGING.120.010931
41. Palma E. M. S., Reis de Sousa A., Andrade de Morais F., Evangelista Luz R., Freitas Neto Á. L., Lima P. P. F. Coping moderates the relationship between intolerance of uncertainty and stress in men during the COVID-19 pandemic. Revista da Escola de Enfermagem da USP, 2022, 56. doi: 10.1590/1980-220X-REEUSP-2021-0303
42. Paschou S. A., Psaltopoulou T., Halvatsiotis P., Raptis A., Vlachopoulos C. V., Dimopoulos M.-A. Gender differences in COVID-19. Maturitas, 2022, 161: 72–73. doi: 10.1016/j.maturitas.2022.03.004
43. Rosenqvist E., Kiviruusu O., Berg N., Konttinen H. Stress-induced eating and drinking and their associations with weight among women and men during 30-year follow-up. Psychology & Health, 2025, 40(1). doi: 10.1080/08870446.2023.2192240
44. Staneva A., Carmignani F., Rohde N. Personality, gender, and age resilience to the mental health effects of COVID-19. Social Science & Medicine, 2022, 301. doi: 10.1016/j.socscimed.2022.114884
45. Steptoe A., Frank P. Obesity and psychological distress. Philosophical Transactions of the Royal Society B. Biological Sciences, 2023, 378(1888). doi: 10.1098/rstb.2022.0225
46. Tacchini-Jacquier N., Bonvin E., Monnay S., Verloo H. Perceived stress, trust, safety and severity of SARS-CoV-2 infection among patients discharged from hospital during the COVID-19 pandemic's first wave: A PREMs survey. BMJ Open, 2022, 12(6). doi: 10.1136/bmjopen-2021-060559
47. Tordjman S. Aggressive behavior: A language to be understood. L’Encéphale, 2022, 48(Suppl_1): S4–S13. doi: 10.1016/j.encep.2022.08.007
48. Tsigos C., Chrousos G. P. Hypothalamic-pituitary-adrenal axis, neuroendocrine factors and stress. Journal of Psychosomatic Research, 2002, 53(4): 865–871. doi: 10.1016/s0022-3999(02)00429-4
49. Xie Q., Liu X.-B., Xu Y.-M., Zhong B.-L. Understanding the psychiatric symptoms of COVID-19: A meta-analysis of studies assessing psychiatric symptoms in Chinese patients with and survivors of COVID-19 and SARS by using the Symptom Checklist-90-Revised. Translational Psychiatry, 2021, 11. doi: 10.1038/s41398-021-01416-5
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For citations:
Guskova O.A., Prilensky B.Yu., Stoyanova I.Ya., Yaroslavskaya E.I., Avdeeva K.S., Petelina T.I. Medical and Psychological Distress in Male COVID-19 Survivors with Lung Damage. SibScript. 2025;27(2):149-162. (In Russ.) https://doi.org/10.21603/sibscript-2025-27-2-149-162. EDN: oujdwa