HLA DRB1 INFLUENCE ON FEMALE SUBJECTIVE EVALUATION OF YOUNG MEN ODOR
Abstract
Olfactory testing is organized in group unmarried students volunteer. The donors of the scent were 48 youths, but recipients of the scent - 19 girls. The samples of the perspiration were collecting by method described by Moshkin M. P. (2009). All young people were typed for their HLA-DRB1. The study has shown that particularities of olfactory estimations woman mans are connected with man's genotype and woman's ovulatory phase. The negative olfactory assessment are connected with combination feminine HLA-DRB1*04 and male HLA-DRB1*15 associated with immunopathology.
About the Authors
Аnna Alexandrovna Mogilina
Institute of Integrated Problems of Cardiovascular Diseases, Siberian Branch of the Russian Academy of Medical Sciences
Russian Federation
Russian Federation
Andrei Vladimirovich Shabaldin
Institute of Computational Technologies of SB RAS
Russian Federation
Russian Federation
Nadezda Alekseevna Litvinova
KemSU
Russian Federation
Russian Federation
Vadim Ivanovich Ivanov
KemSU
Russian Federation
Russian Federation
Liliya Vladimirovna Akinchina
Human Ecology Institute of SB RAS
Russian Federation
Russian Federation
References
1. Yamazaki, K. Recognition among mice evidanse from the use of Y-mase dofferentially scented by congenic mice of different histocompatibility complex / K. Yamazaki, M. Yamaguchi, L. Baranoski, J. Bard, E. A. Boyse, L. Thomas // J. Exp. Med. - 1979. - V. 150. - P. 755.
2. Doherty, P. C. Enhanced immunological surveillance in mice heterozygous at the H-2 gene complex / P. C. Doherty, R. M. Zinkernagel // Nature. - 1975. - V. 256 - P. 50 - 52.
3. Wysocki, C. J. Mice (Mus musculus) lacking a vomeronasal organ can discriminate MHC-determined odortypes / C. J. Wysocki, K. Yamazaki, M. Curran, L. M. Wysocki, G. K. Beauchamp // Horm. Behav. -2004. -V. 46. - № 3. - P. 241 - 246.
4. Thomas, L. Symbiosis as an immunologic problem / L. Thomas. - Basel: S. Karger, 1975. - P. 2 - 11.
5. Yamazaki, K. Sensory distinction between H-2b and H-2 bm1 mutant mice / K. Ymazaki, G. K. Beauchamp, I. K. Egorov, J. Bard, E. A. Boyse // Proc Natl Acad Sci USA. -1983. - V. 80. - P. 5685 - 5688.
6. Киндт, Т. Дж Антигены главного комплекса гистосовместимости / Т. Дж. Киндт, М. Э. Робинсон // Иммунология, под ред. У. Пола. - М., 1988 - Т. 2 - С. 73 - 116.
7. Preti, G. Male axillary extracts effect Lutenizing Hormon pulsing in female recipients / G. Preti, C. J. Wysocki, K. Barnhart, S. J. Sonheimer, J. J. Leyden // Poster presentation at the 23rd Association for Chemoreception Sciences annual Meeting. - 2001.
8. Wedekind, C. MHC-dependent mate preference in humans / C. Wedekind, T. Seebeck, F. Bettens, A. Paepke // Proc. R. Soc. Lond. B. - 1995. - V. 260. - P. 245 - 249.
9. Wedekind, C. Body odour preferences in men and women: do they aim for specifi c MHC combinations or simply heterozygosity? / C. Wedekind, S. Furi // Proc. R. Soc. Lond. B. Biol. Sci. - 1997. - V. 264. - № 1387. - P. 1471 - 1479.
10. Wedekind, C. The Major Histocompatibility Complex and Perfumers' Descriptions of Human Body Odors / C. Wedekind, S. Escher, M. Van de Waal, E. Frei // Evolutionary Psychology. - 2007. - ISSN 1474 - 7049. - V. 5(2). - P. 330 - 343.
11. Ober, C. HLA and mate choice in humans / C. Ober, L. R. Weitkamp, N. Cox, H. Dytch, D. Kostyu, S. Elias // Am. J. Hum. Genet. - 1997. - № 61. - P. 497 - 504.
12. Hedrick, P. W. HLA and mate selection: No evidence in South Amerindians / P. W. Hedrick, F. L. Black // Am. J. Hum. Genet. - 1997. - № 61. - Р. 505 - 511.
13. Ihara, Y. HLA and human mate choice: Tests on Japanese couples / Y. Ihara, K. Aoki, K. Tokunaga, K. Takahashi, T. Juji // Anthropological Science. - 2000. - 108 - 199 - 214.
14. Штейн, М. А. Ассортативный подбор супружеских пар по локусу HLA-DR / М. А. Штейн, А. В. Шабалдин, А. Н. Глушков, Л. А. Логинова // Иммунология. - 2002. - № 1. - С. 26 - 28.
15. Cutler, W. B. Human Axillary Secretions Inf1uence Women's Меnstrua1 Cyc1es: Тhе Ro1e of Donor Extract from Меn / W. B. Cutler, G. Preti, A. Krieger, G. R. Huggins, C. R. Garcia, R. J. Lawley // Horm. Веhаv. - 1986. - Vol. 20. - Р. 463 - 473.
16. Wysocki, C. J. Mice (Mus musculus) lacking a vomeronasal organ can discriminate MHC-determined odortypes / C. J. Wysocki, K. Yamazaki, M. Curran, L. M. Wysocki, G. K. Beauchamp // Horm. Behav. -2004. -V. 46. - № 3. - P. 241 - 246.
17. Мошкин, М. П. Изменение запаха у студентов мужского пола в стрессирующей ситуации / М. П. Мошкин, Л. А. Герлинская, И. Е. Колосова, Н. А. Литвинова, Л. А. Саваль, М. Г. Березина // Российский физиологический журнал им. И. М. Сеченова. - 2006. - Т. 92. - № 10.
18. Rantala, М. J. Маlе Steroid Hormones and Ретаlе Preference for Маlе Body Odor / М. J. Rantala, С. J. Р. Eriksson, А. Vainikka, R. Kortet // Evol. & Нит. Веhаv. - 2006. - Vol. 27. - Р. 259 - 269.
19. Sheldon, М. S. Fertility Сусlе Patterns in Motives for Sexual Sehavior / М. S. Sheldon, М. L. Cooper, D. С. Geary, М. Hoard, М. С. DeSoto // Pers. Soc. Psychol. ВиН. - 2006. - Vоl. 32. - Р. 1659 - 1673.
20. Молекулярная клиническая диагностика. Методы / под ред. С. Херрингтона. - М.: Мир, 1999.
21. Болдырева, М. Н. HLA и естественный отбор. Гипотеза «преимущества функциональной гетерозиготности» / М. Н. Болдырева, Л. П. Алексеев // Иммунология. - М., 2006. - № 3. - С. 172 - 175.
22. Schipper, R. F. HLA class II associations with Type 1 diabetesmellitus: a multivariate approach / R. F. Schipper, B. P. Koeleman, G. J. Bruining, G. M. Schreuder, W. Verduijn, R. R. Vries, B. O. Roep // Tissue Antigens. - 2001. - Vol. 57(2). -P. 144 - 50.
23. Zanelli, E. Evidence alternate splicing in the thyroperoxidase messenger patients with Graves' disease / E. Zanelli, M. Henry, B. Charvet, Y. Malthiery // Biochem. Biophys. - 1990. - № 17. - P. 735 - 41.
24. Hunt, P. J. Histocompatibility leucocyte antigens and closely linked immunomodulatory genes in autoimmune thyroid disease / P. J. Hunt, S. E. Marshall, A. P. Weetman, M. Bunce, J. I. Bell, J. A. Wass, K. I. Welsh // Clin Endocrinol (Oxf). - 2001. - 55(4):491 - 9.
25. Болдырева, М. Н. HLA (класс II) и естественный отбор. «Функциональный» генотип, гипотеза преимущества «функциональной» гетерозиготности / М. Н. Болдырева: диссертационная работа на соискание докторской степени. - М., 2007. - 154 с.
26. Tektonidou, M. Antiphospholipd syndrome / M. Tektonidou // Orphanet encyclopedia. - URL: http://www.orpha.net/data/patho/GB/uk-APS.pdf.
27. Khomenko, A. G. Tuberculosis in patients with various HLA Phenotypes / A. G. Khomenko, V. I. Litvinov, V. P. Chukanova, L. E. Pospelov // Tubercle. - 1990. - V. 71. - P. 187.
28. Singer, A. G. Volatile signals of the major histocompatibility complex in male mouse urine / A. G. Singer, G. K. Beauchamp, K. Yamazaki // Proc. Natl. Acad. Sci. USA. - 1997. - Vol. 94. - P. 2210 - 2214.
29. Yamazaki, K. HLA-B transgenic mice roduce a unique odor type / K. Ymazaki, G. K. Beauchamp, J. Bard, E. Lacy, E. A. Boyse // Behav Genet. - 1990. - V. 20. - 755 p.
30. Wobst, B. Molecular forms of soluble HLA in body fluids; potential determents of body odor cues / B. Wobst, N. Zavazava, D. Luscyk, K. Lange, S. Ussat, F. Eggert, R. Ferstl, W. Muller-Ruchholtz // Genetica. - 1999. - V. 104. - P. 275 - 283.
Review
For citations:
Mogilina А.A., Shabaldin A.V., Litvinova N.A., Ivanov V.I., Akinchina L.V. HLA DRB1 INFLUENCE ON FEMALE SUBJECTIVE EVALUATION OF YOUNG MEN ODOR. The Bulletin of Kemerovo State University. 2011;(4):6-12. (In Russ.)
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