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POLYMORPHISM OF TWO LIG4 GENETIC MARKERS IN THE INDIGENOUS AND MIGRANT POPULATION OF KEMEROVO REGION

Abstract

The population genetic characteristics of two LIG4 polymorphic markers were examined in the indigenous (the Shors) and migrant (the Russians) population of Kemerovo region. The frequencies of genetic variants of Ala3Val polymorphism did not differ significantly between the two groups. At the same time a significant difference of the genotypes and allele polymorphism of Thr9Ile distributions between the ethnic cohorts was revealed. Minor allele Ile frequency among the representatives of the migrant population was almost three times as high as that of theindigenous ethnic group.

About the Authors

A. N. Volkov
Kemerovo State Medical Academy
Russian Federation
Aleksey N. Volkov – Candidate of Biology, Assistant Professor at the Department of Genetics, Kemerovo State University; senior researcher at the Central Research Laboratory


A. I. Martinyuk
Kemerovo State Medical Academy
Russian Federation
Aleksander I. Martinyuk – post-graduate student at the Department of Genetics


A. V. Larionov
Kemerovo State Medical Academy
Russian Federation
Alexey V. Larionov – engineer at the Department of Genetics


D. K. Shihkova
Kemerovo State Medical Academy
Russian Federation
Darya K. Shishkova – 5th-year student at the Biological Faculty


V. I. Minina
Kemerovo State University; Institute for Human Ecology of the Siberian branch of the RAS
Russian Federation
Varvara I. Minina – Candidate of Biology, Assistant Professor at the Department of Genetics, Kemerovo State University; senior researcher at the Institute for Human Ecology of the Siberian branch of the RAS


A. A. Timopheeva
Kemerovo State University; Institute for Human Ecology of the Siberian branch of the RAS
Russian Federation
Anna A. Timofeeva – post-graduate student at the Department of Genetics, Kemerovo State University; engineer at theInstitute for Human Ecology of the Siberian branch of the RAS


V. G. Druzhinin
Kemerovo State University; Institute for Human Ecology of the Siberian branch of the RAS
Russian Federation
Vladimir G. Druzhinin – Doctor of Biology, Professor, Head of the Department of Genetics, Kemerovo State University; leading researcher at the Institute for Human Ecology of the Siberian branch of the RAS


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Review

For citations:


Volkov A.N., Martinyuk A.I., Larionov A.V., Shihkova D.K., Minina V.I., Timopheeva A.A., Druzhinin V.G. POLYMORPHISM OF TWO LIG4 GENETIC MARKERS IN THE INDIGENOUS AND MIGRANT POPULATION OF KEMEROVO REGION. SibScript. 2013;(1):12-15. (In Russ.)

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ISSN 2949-2122 (Print)
ISSN 2949-2092 (Online)