kemsuСибСкриптSibScript2949-21222949-2092Kemerovo State Universitykemsu-3882Research ArticleСтатьиМОЛЕКУЛЯРНО-ГЕНЕТИЧЕСКИЙ АНАЛИЗ ПОЛИМОРФИЗМА ГЕНОВ hOGG1 И ADPRT У КОРЕННОГО И ПРИШЛОГО НАСЕЛЕНИЯ ТАШТАГОЛЬСКОГО РАЙОНА КЕМЕРОВСКОЙ ОБЛАСТИMOLECULAR GENETIC ANALYSIS OF hOGG1 and ADPRT POLYMORPHISM AMONG INDIGENOUS AND MIGRANT POPULATIONS OF THE KEMEROVO REGIONМининаВарвара ИвановнаMininaVarvara Ivanovnavminina@mail.ru <mailto:vminina@mail.ru>ДружининВладимир ГеннадьевичDruzhininVladimir Gennadievichdruzhinin_vladim@mail.ru <mailto:druzhinin_vladim@mail.ru>ГлушковАндрей НиколаевичGlushkovAndrey Nikolayevichnoemail@neicon.ruТимофееваАнна АлександровнаTimopheevaAnna Aleksandrovnacoldunica@mail.ruЛарионовАлексей ВикторовичLarionovAlexey Viktorovichnoemail@neicon.ruКемГУРоссияKemSURussian FederationИнститут экологии человека СО РАНРоссияInstitute of Human Еcology SB RASRussian Federation2011231020110369Copyright &#x00A9; Минина В.И., Дружинин В.Г., Глушков А.Н., Тимофеева А.А., Ларионов А.В., 20112011Минина В.И., Дружинин В.Г., Глушков А.Н., Тимофеева А.А., Ларионов А.В.Minina V.I., Druzhinin V.G., Glushkov A.N., Timopheeva A.A., Larionov A.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.sibscript.ru/jour/article/view/3882

Проведено исследование полиморфизма генов hOGG1Ser326Cys и ADPRT Val762Ala в выборках представителей двух этносов, проживающих в Таштагольском районе Кемеровской области (шорцы, русские). Частота встречаемости минорных аллелей: hOGG1 Cys и ADPRT Ala в группе шорцев соответствуют данным, полученным для монголоидов (в различных популяциях мира) и статистически значимо превышает встречаемость этих аллелей в группе русских Кемеровской области. Эти данные свидетельствует о большом удельном весе монголоидного компонента в генофонде коренного малочисленного народа Сибири - шорцев.

Gene polymorphism hOGG1Ser326Cys and ADPRT Val762Ala in two ethnic groups of the Kemerovo region (Shors, Russian) has been studied. The frequency of minor alleles: hOGG1 Cys and ADPRT Ala group Shors corresponds to data obtained for Mongoloid (in various world populations) and significantly higher than the incidence of these alleles in a group of Russian Kemerovo region. These data indicate a high specific weight of the Mongoloid component in the genome of the indigenous people of Siberia - Shor.

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The authors declare that there are no conflicts of interest present.