kemsuСибСкриптSibScript2949-21222949-2092Kemerovo State University10.21603/2078-8975-2019-21-1-56-65kemsu-2648Research ArticleПсихологияPsychologyАнализ нейрокогнитивного развития детей со средней и легкой степенью недоношенности в раннем возрасте с помощью шкал Бейли (третья редакция)Analysis of Neurocognitive Development of Moderate and Late Preterm Children in Early Childhood Using Bayley-IIIБакушкинаН. И.BakushkinaN. I.

620002, Россия, г. Екатеринбург, ул. Мира, 19

http://www.researcherid.com/rid/D-6985-2019

19, Mira St., Yekaterinburg, Russia, 620002

http://www.researcherid.com/rid/D-6985-2019

https://orcid.org/0000-0002-1259-7567РогачеваТ. В.RogachevaT. V.

620089, Россия, г. Екатеринбург, ул. Белинского, 173 А

173 A, Belinskiy St., Yekaterinburg, Russia, 620089

TVRog@yandex.ruУральский федеральный университет им. первого Президента России Б. Н. ЕльцинаРоссияB. N. Yeltsin Ural Federal UniversityRussian FederationОбластной центр реабилитации инвалидовРоссияRegional Center for Rehabilitation of Disabled PersonsRussian Federation2019210520192115665Copyright © Бакушкина Н.И., Рогачева Т.В., 20192019Бакушкина Н.И., Рогачева Т.В.Bakushkina N.I., Rogacheva T.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.sibscript.ru/jour/article/view/2648

В статье приведены данные эмпирического исследования развития нейрокогнитивных функций у детей со средней и легкой степенью недоношенности в возрасте 3, 5, 10, 14 и 25 месяцев. На сегодняшний день данная популяция детей составляет 75–80 % от общего числа недоношенных, но при этом данной группе не уделяется достаточное внимание со стороны специалистов разных профилей, что ограничивает количество информации относительно их нейрокогнитивного развития, хотя раннее рождение на любом сроке гестации дает право относить ребенка к группе риска развития тех или иных отклонений. Неоспоримым является тот факт, что раннее рождение оказывает определенное воздействие на развитие мозга младенца, влияя на важные процессы дифференциации нейронов, миелинизации, синаптогенеза и др. Для исследования нейрокогнитивных функций была использована поведенческая методика шкал Бейли третьей редакции (Bayley-III), благодаря которой можно оценить когнитивное развитие, развитие рецептивной и экспрессивной коммуникации, а также мелкой и крупной моторики. Показано, что недоношенность легкой и средней степени оказывает избирательное влияние на развитие нейрокогнитивных функций, а степень влияния зависит от этапа онтогенеза и сферы развития. 

The article features an empirical study of the development of neurocognitive functions in moderate and late preterm children at the age of 3, 5, 10, 14, and 25 months. To date, this population of infants is 75–80 % of the total number of premature infants, but specialists of different profiles do not give enough attention to this group of children, which limits the amount of information regarding their neurocognitive development, in spite of the fact that prematurity at any gestation period gives the right to refer the child to a risk group of different impairments. Premature birth has a certain impact on the development of the infant’s brain, affecting the important processes of differentiation of neurons, myelination, synaptogenesis, etc. Neurocognitive functions were measured by the Bayley Scales behavioral technique, third edition (Bayley-III). The technique makes it possible to assess the cognitive development, the development of receptive and expressive communication, as well as fine and gross motor skills. The research demonstrated that moderate and late prematurity has a selective effect on the development of neurocognitive functions, and the degree of impact depends on the stage of ontogenesis and the sphere of development.

нейрокогнитивные функциираннее развитиегестациянедоношенностькогнитивное развитиеречевое развитиемоторное развитиеneurocognitive functionsearly developmentgestationprematuritycognitive developmentlanguage developmentmotor developmentReferencesMuglia L. J., Katz M. The enigma of spontaneous preterm birth // The New England Journal of Medicine. 2010. Vol. 362. № 6. P. 529–535. DOI: https://doi.org/10.1056/NEJMra0904308Muglia L. J., Katz M. The enigma of spontaneous preterm birth. The New England Journal of Medicine, 2010, 362(6): 529–535. DOI: https://doi.org/10.1056/NEJMra0904308Кузьминых Т. У., Арутюнян А. В., Прокопенко В. М. Новые подходы к лечению женщин с угрозой преждевременного прерывания беременности // Вестник Российской ассоциации акушеров-гинекологов. 1997. № 3. С. 49–51.Kuzminykh T. U., Arutiunian A. V., Prokopenko V. M. New approaches to the treatment of women with the threat of premature termination of pregnancy. Vestnik Rossiiskoi assotsiatsii akusherov-ginekologov, 1997, (3): 49–51. (In Russ.)Stephens B. E., Vohr B. R. Neurodevelopmental outcome of the premature infant // Pediatric Clinics of North America. 2009. Vol. 56. Iss. 3. P. 631–646. DOI: https://doi.org/10.1016/j.pcl.2009.03.005Stephens B. E., Vohr B. R. Neurodevelopmental outcome of the premature infant. Pediatric Clinics of North America, 2009, 56(3): 631–646. DOI: https://doi.org/10.1016/j.pcl.2009.03.005McGrath M. M., Sullivan M. C., Lester B. M., Oh W. Longitudinal neurologic follow-up in neonatal intensive care unit survivors with various neonatal morbidities // Pediatrics. 2000. Vol. 106. Iss. 6. P. 1397–1405. DOI: https://doi.org/10.1542/peds.106.6.1397McGrath M. M., Sullivan M. C., Lester B. M., Oh W. Longitudinal neurologic follow-up in neonatal intensive care unit survivors with various neonatal morbidities. Pediatrics, 2000, 106(6): 1397–1405. DOI: https://doi.org/10.1542/peds.106.6.1397Волгина С. Я., Менделевич В. Д. Нервно-психическое развитие недоношенных детей в отдаленные периоды жизни // Неврологический вестник. 2001. Т. XXXIII. № 3-4. С. 84–88.Volgina S. A., Mendelevich V. D. Neuropsychiatric development of premature infants in remote periods of life. Neurological Bulletin, 2001, (3-4): 84–88. (In Russ.)Johnson S., Marlow N. Early and long-term outcome of infants born extremely preterm // Archives of Disease in Childhood. 2016. Vol. 102. Iss. 1. P. 97–102. DOI: https://doi.org/10.1136/archdischild-2015-309581Johnson S., Marlow N. Early and long-term outcome of infants born extremely preterm. Archives of Disease in Childhood, 2016, 102(1): 97–102. DOI: https://doi.org/10.1136/archdischild-2015-309581Glass H., Costarino A., Stayer S., Brett C., Cladis F., Davis P. Outcomes for Extremely Premature Infants // Anesthesia & Analgesia. 2015. Vol. 120(6). P. 1337–1351. DOI: https://doi.org/10.1213/ane.0000000000000705Glass H., Costarino A., Stayer S., Brett C., Cladis F., Davis P. Outcomes for Extremely Premature Infants. Anesthesia & Analgesia, 2015, 120(6): 1337–1351. DOI: https://doi.org/10.1213/ane.0000000000000705Khashu M., Narayanan M., Bhargava S., Osiovich H. Perinatal outcomes associated with preterm birth at 33 to 36 weeks’ gestation: a population-based cohort study // Pediatrics. 2009. Vol. 123. Iss. 1. P. 109–113. DOI: https://doi.org/10.1542/peds.2007-3743Khashu M., Narayanan M., Bhargava S., Osiovich H. Perinatal outcomes associated with preterm birth at 33 to 36 weeks’ gestation: a population-based cohort study. Pediatrics, 2009, 123(1): 109–113. DOI: https://doi.Kitsommart R., Janes M., Mahajan V., Rahman A., Seidlitz W., Wilson J., Paes B. Outcomes of Late-Preterm Infants: A Retrospective, Single-Center, Canadian Study // Clinical Pediatrics. 2009. Vol. 48. Iss. 8. P. 844–850. DOI: https://doi.org/10.1177/0009922809340432org/10.1542/peds.2007-3743Васильева М. Ю., Чернего Д. И., Мухамедрахимов Р. Ж. Психическое развитие недоношенных детей первого года жизни, воспитывающихся в семьях и домах ребенка // Вестник Санкт-Петербургского университета. Серия 12. Психология. Социология. Педагогика. 2010. № 4. С. 193–201.Kitsommart R., Janes M., Mahajan V., Rahman A., Seidlitz W., Wilson J., Paes B. Outcomes of Late-Preterm Infants: A Retrospective, Single-Center, Canadian Study. Clinical Pediatrics, 2009, 48(8): 844–850. DOI: https://doi.Kugelman A., Colin A. A. Late Preterm Infants: Near Term But Still in a Critical Developmental Time Period // Pediatrics. 2013. Vol. 132. Iss. 4. P. 741–751. DOI: https://doi.org/10.1542/peds.2013-1131org/10.1177/0009922809340432Petrini J. R., Dias T., McCormick M. C., Massolo M. L., Green N. S., Escobar G. J. Increased Risk of Adverse Neurological Development for Late Preterm Infants // The Journal of Pediatrics. 2009. Vol. 154. Iss. 2. P. 169–176.e3. DOI: https://doi.org/10.1016/j.jpeds.2008.08.020Vasilyeva M. J., Chernego D. I., Mukhamedrakhimov R. J. Developmental status of preterm infants living in families and orphanages during their first year of life. Vestnik Sankt-Peterburgskogo universiteta. Seriia 12. Psikhologiia. Sotsiologiia. Pedagogika, 2010, (4): 193–201. (In Russ.)Blencowe H., Lee A. C., Cousens S., Bahalim A., Narwal R., Zhong N., Chou D., Say L., Modi N., Katz J., Vos Th., Marlow N., Lawn J. E. Preterm birth-associated neurodevelopmental impairment estimates at regional and global levels for 2010 // Pediatric Research. 2013. Vol. 74(S1). P. 17–34. DOI: https://doi.org/10.1038/pr.2013.204Kugelman A., Colin A. A. Late Preterm Infants: Near Term But Still in a Critical Developmental Time Period. Pediatrics, 2013, 132(4): 741–751. DOI: https://doi.org/10.1542/peds.2013-1131Escobar G. J., Clark R. H., Greene J. D. Short-Term Outcomes of Infants Born at 35 and 36 Weeks Gestation: We Need to Ask More Questions // Seminars in Perinatology. 2006. Vol. 30. Iss. 1. P. 28–33. DOI: https://doi.org/10.1053/j.semperi.2006.01.005Petrini J. R., Dias T., McCormick M. C., Massolo M. L., Green N. S., Escobar G. J. Increased Risk of Adverse Neurological Development for Late Preterm Infants. The Journal of Pediatrics, 2009, 154(2): 169–176.e3. DOI: https://doi.org/10.1016/j.jpeds.2008.08.020Williams J., Pugh Y. The Late Preterm // Critical Care Nursing Clinics of North America. 2018. Vol. 30. Iss. 4. P. 431–443.Blencowe H., Lee A. C., Cousens S., Bahalim A., Narwal R., Zhong N., Chou D., Say L., Modi N., Katz J., Vos Th., Marlow N., Lawn J. E. Preterm birth-associated neurodevelopmental impairment estimates at regional and global levels for 2010. Pediatric Research, 2013, 74(S1): 17–34. DOI: https://doi.org/10.1038/pr.2013.204Blencowe H., Cousens S., Chou D., Oestergaard M., Say L., Moller A.-B., Kinney M., Lawn J. Born Too Soon: The global epidemiology of 15 million preterm births // Reproductive Health. 2013. Vol. 10 (Suppl 1). S2. DOI: https://doi.org/10.1186/1742-4755-10-s1-s2Escobar G. J., Clark R. H., Greene J. D. Short-Term Outcomes of Infants Born at 35 and 36 Weeks Gestation: We Need to Ask More Questions. Seminars in Perinatology, 2006, 30(1): 28–33. DOI: https://doi.org/10.1053/j.semperi.2006.01.005Gill J. V., Boyle E. M. Outcomes of infants born near term // Archives of Disease in Childhood. 2016. Vol. 102. Iss. 2. P. 194–198. DOI: https://doi.org/10.1136/archdischild-2015-309584Williams J., Pugh Y. The Late Preterm. Critical Care Nursing Clinics of North America, 2018, 30(4): 431–443.Altimier L., Phillips R. M. The Neonatal Integrative Developmental Care Model: Seven Neuroprotective Core Measures for Family-Centered Developmental Care // Newborn and Infant Nursing Reviews. 2013. Vol. 13. Iss. 1. P. 9–22. DOI: https://doi.org/10.1053/j.nainr.2012.12.002Blencowe H., Cousens S., Chou D., Oestergaard M., Say L., Moller A.-B., Kinney M., Lawn J. Born Too Soon: The global epidemiology of 15 million preterm births. Reproductive Health, 2013, 10(1): S2. DOI: https://doi.Tau G. Z., Peterson B. S. Normal development of brain circuits // Neuropsychopharmacology. 2010. Vol. 35. P. 147–168. DOI: https://doi.org/10.1038/npp.2009.115org/10.1186/1742-4755-10-s1-s2Webb S. J., Monk C. S., Nelson Ch. A. Mechanisms of Postnatal Neurobiological Development: Implications for Human Development // Developmental Neuropsychology. 2001. Vol. 19. Iss. 2. P. 147–171. DOI: https://doi.org/10.1207/s15326942dn1902_2Gill J. V., Boyle E. M. Outcomes of infants born near term. Archives of Disease in Childhood, 2016, 102(2): 194–198. DOI: https://doi.org/10.1136/archdischild-2015-309584Volpe J. J. Neurology of the Newborn. 4th ed. PA: Saunders Elsevier, 2008. 715 p.Altimier L., Phillips R. M. The Neonatal Integrative Developmental Care Model: Seven Neuroprotective Core Measures for Family-Centered Developmental Care. Newborn and Infant Nursing Reviews, 2013, 13(1): 9–22. DOI: https://doi.org/10.1053/j.nainr.2012.12.002Петрухин А. С. Неврология детского возраста. М.: Медицина, 2004. 784 с.Tau G. Z., Peterson B. S. Normal development of brain circuits. Neuropsychopharmacology, 2010, (35): 147–168. DOI: https://doi.org/10.1038/npp.2009.115Скворцов И. А., Ермоленко Н. А. Развитие нервной системы детей в норме и патологии. М.: МЕДпресс-информ, 2003. 367 с.Webb S. J., Monk C. S., Nelson Ch. A. Mechanisms of Postnatal Neurobiological Development: Implications for Human Development. Developmental Neuropsychology, 2001, 19(2): 147–171. DOI: https://doi.org/10.1207/s15326942dn1902_2Volpe J. J. Brain injury in premature infants: a complex amalgam of destructive and developmental disturbances // Lancet Neurol. 2009. Vol. 8. P. 110–124.Volpe J. J. Neurology of the Newborn. 4th ed. PA: Saunders Elsevier, 2008, 715.Escobar G. J., Greene J. D., Hulac P., Kincannon N., Bischoff H., Gardner M. N., Armstrong M. A., France E. K. Rehospitalisation after birth hospitalisation: patterns among infants of all gestations // Archives of Disease in Childhood. 2005. Vol. 90. Iss. 2. P. 125–131. DOI: https://doi.org/10.1136/adc.2003.039974Petruhin A. S. Neurology of childhood. Moscow: Meditsina, 2004, 784. (In Russ.)Eryigit-Madzwamuse S., Strauss V., Baumann N., Bartmann P., Wolke D. Personality of adults who were born very preterm // ADC Fetal & Neonatal. 2015. Vol. 100. Iss. 6. P. F524–F529. DOI: https://doi.org/10.1136/archdischild-2014-308007Skvortsov I. A., Ermolenko N. A. Development of children’s nervous system in norm and pathology. Moscow: MEDpressinform, 2003, 367. (In Russ.)Breeman L. D., Jaekel J., Baumann N., Bartmann P., Wolke D. Preterm Cognitive Function Into Adulthood // Pediatrics. 2015. Vol. 136. Iss. 3. P. 415–423. DOI: https://doi.org/10.1542/peds.2015-0608Volpe J. J. Brain injury in premature infants: a complex amalgam of destructive and developmental disturbances. Lancet Neurol, 2009, (8): 110–124.Bradfield L. Core Curriculum for Neonatal Intensive Care Nursing // Nurse Education in Practice. 2010. Vol. 10. Iss. 6. P. e59. DOI: https://doi.org/10.1016/j.nepr.2010.04.001Escobar G. J., Greene J. D., Hulac P., Kincannon N., Bischoff H., Gardner M. N., Armstrong M. A., France E. K. Rehospitalisation after birth hospitalisation: patterns among infants of all gestations. Archives of Disease in Childhood, 2005, 90(2): 125–131. DOI: https://doi.org/10.1136/adc.2003.039974Bayley N. Bayley scales of infant and toddler development. 3rd ed. San Antonio, TX: Harcourt Assessment, 2006. 267 p.Eryigit-Madzwamuse S., Strauss V., Baumann N., Bartmann P., Wolke D. Personality of adults who were born very preterm. ADC Fetal & Neonatal, 2015,100(6): F524–F529. DOI: https://doi.org/10.1136/archdischild-2014-308007Weiss L., Oakland T., Aylward G. Bayley-III, clinical use and interpretation. London: Elsevier, 2010. 240 p.Breeman L. D., Jaekel J., Baumann N., Bartmann P., Wolke D. Preterm Cognitive Function Into Adulthood. Pediatrics, 2015, 136(3): 415–423. DOI: https://doi.org/10.1542/peds.2015-0608Adams-Chapman I., Bann C. M., Vaucher Y. E., Stoll B. J. Association between Feeding Difficulties and Language Delay in Preterm Infants Using Bayley Scales of Infant Development-Third Edition // The Journal of Pediatrics. 2013. Vol. 163. Iss. 3. P. 680–685.e3. DOI: https://doi.org/10.1016/j.jpeds.2013.03.006Bradfield L. Core Curriculum for Neonatal Intensive Care Nursing. Nurse Education in Practice, 2010, 10(6): e59. DOI: https://doi.org/10.1016/j.nepr.2010.04.001Steenis L. J. P., Verhoeven M., Hessen D. J., Baar van A. L. Performance of Dutch Children on the Bayley III: A Comparison Study of US and Dutch Norms // PLOS ONE. 2015. Vol. 10. Iss. 8. P. e0132871. DOI: https://doi.org/10.1371/journal.pone.0132871Bayley N. Bayley scales of infant and toddler development. 3rd ed. San Antonio, TX: Harcourt Assessment, 2006, 267.Simpson S., D’Aprano A., Tayler C., Toon Khoo S., Highfold R. Validation of a culturally adapted developmental screening tool for Australian Aboriginal children: Early findings and next steps // Early Human Development. 2016. Vol. 103. P. 91–95. DOI: https://doi.org/10.1016/j.earlhumdev.2016.08.005Weiss L., Oakland T., Aylward G. Bayley-III, clinical use and interpretation. London: Elsevier, 2010, 240.Hanlon C., Medhin G., Worku B., Tomlinson M., Alem A., Dewey M., Prince M. Adapting the Bayley Scales of infant and toddler development in Ethiopia: evaluation of reliability and validity // Child: Care, Health and Development. 2016. Vol. 42. Iss. 5. P. 699–708. DOI: https://doi.org/10.1111/cch.12371Adams-Chapman I., Bann C. M., Vaucher Y. E., Stoll B. J. Association between Feeding Difficulties and Language Delay in Preterm Infants Using Bayley Scales of Infant Development-Third Edition. The Journal of Pediatrics, 2013, 163(3): 680–685.e3. DOI: https://doi.org/10.1016/j.jpeds.2013.03.006Hicks M. S., Sauve R. S., Robertson C. M. T., Joffe A. R., Alton G., Creighton G., Boss D. B., Rebeyka I. M. Early childhood language outcomes after arterial switch operation: a prospective cohort study // SpringerPlus. 2016. Vol. 5. Iss. 1. P. 1681. DOI: https://doi.org/10.1186/s40064-016-3344-5Steenis L. J. P., Verhoeven M., Hessen D. J., Baar van A. L. Performance of Dutch Children on the Bayley III: A Comparison Study of US and Dutch Norms. PLOS ONE, 2015, 10(8): e0132871. DOI: https://doi.org/10.1371/journal.pone.0132871Kirchner R. M., Martens M. A., Andridge R. R. Adaptive Behavior and Development of Infants and Toddlers with Williams Syndrome // Frontiers in Psychology. 2016. Vol. 7. DOI: https://doi.org/10.3389/fpsyg.2016.00598Simpson S., D’Aprano A., Tayler C., Toon Khoo S., Highfold R. Validation of a culturally adapted developmental screening tool for Australian Aboriginal children: Early findings and next steps. Early Human Development, 2016, (103): 91–95. DOI: https://doi.org/10.1016/j.earlhumdev.2016.08.005Hanlon C., Medhin G., Worku B., Tomlinson M., Alem A., Dewey M., Prince M. Adapting the Bayley Scales of infant and toddler development in Ethiopia: evaluation of reliability and validity. Child: Care, Health and Development, 2016, 42(5): 699–708. DOI: https://doi.org/10.1111/cch.12371Hanlon C., Medhin G., Worku B., Tomlinson M., Alem A., Dewey M., Prince M. Adapting the Bayley Scales of infant and toddler development in Ethiopia: evaluation of reliability and validity. Child: Care, Health and Development, 2016, 42(5): 699–708. DOI: https://doi.org/10.1111/cch.12371Hicks M. S., Sauve R. S., Robertson C. M. T., Joffe A. R., Alton G., Creighton G., Boss D. B., Rebeyka I. M. Early childhood language outcomes after arterial switch operation: a prospective cohort study. SpringerPlus, 2016, 5(1): 1681. DOI: https://doi.org/10.1186/s40064-016-3344-5Hicks M. S., Sauve R. S., Robertson C. M. T., Joffe A. R., Alton G., Creighton G., Boss D. B., Rebeyka I. M. Early childhood language outcomes after arterial switch operation: a prospective cohort study. SpringerPlus, 2016, 5(1): 1681. DOI: https://doi.org/10.1186/s40064-016-3344-5Kirchner R. M., Martens M. A., Andridge R. R. Adaptive Behavior and Development of Infants and Toddlers with Williams Syndrome. Frontiers in Psychology, 2016, (7). DOI: https://doi.org/10.3389/fpsyg.2016.00598Kirchner R. M., Martens M. A., Andridge R. R. Adaptive Behavior and Development of Infants and Toddlers with Williams Syndrome. Frontiers in Psychology, 2016, (7). DOI: https://doi.org/10.3389/fpsyg.2016.00598

The authors declare that there are no conflicts of interest present.