This work presents the first case of the research of the processes of the West Siberian industry re-evacuation, which is based on archival materials, as well as the research of the problems of industry organization and social sphere, and other consequences caused by the processes. The purpose of the article is to present the research of historical experience in solving the above mentioned problems connected with industrial enterprises and their staffs re-evacuation, which had been held in the West Siberian region. The research is performed in accordance with the historical science’s main principles. It evinces that the questions of re-evacuation of industrial enterprises and their staffs were solved with the use of personal approach and with respect to the current circumstances. The article emphasizes the hardness of the work being performed. It gives the analysis of the social and organizational problems, which arose in process of the relocation of the enterprises and their staffs to new places, as well as the problems occurred to the staffs of defense enterprises, which stayed inWest Siberiaand traces the ways of solving these problems. The author concludes that in spite of the measures, that had been took, there still existed a complex of reasons, and first of all harsh living conditions, which caused the mass outflow of specialists to the liberated areas of the country. In such circumstances even the defense enterprises were subject to acute cadres’ shortage. Especially it concerned engineering and technical personnel. Re-evacuation not only caused the outflow of qualified industrial cadres, but also significantly aggravated the problem of supplying the Siberian economy in whole with specialists.